After the arrest of most of the members of the drug syndicate, the leader behind the organization was never found and is still at large. Tintin, who is enjoying his stay at the palace of the Maharaja, is visited by a Chinese gentleman who brings Tintin a message. However, a poison dart containing the madness poison was struck right into the massager's neck by an unseen marksman. The only clues Tintin received from the now mad messenger is that there's trouble in Shanghai and a man named Mitsuhirato, which is the place where the remaining members of the syndicate remain. So Tintin heads for Shanghai to meet Mitsuhirato, however upon meeting the person Tintin was almost assassinated twice upon his visit in Shanghai. He ends up being saved by a young Chinese man who provides him with a disguise in order for him to not be easily recognized by the syndicate. Who is the mysterious young man who prevented Tintin's death and can Mitsuhirato be trusted?The only way to save those who have been injected with the madness poison is by finding a doctor who can provide an antidote to cure them. However the doctor was kidnapped by the syndicate and is now being held hostage in Hukow outside the border of Shanghai. To make matters more difficult, Mitsuhirato has ordered the Japanese army station at the border of Shanghai to arrest Tintin if seen trying to exit the border of Shanghai. Tintin, will have to try to escape from Shanghai and head for Hukow to save the doctor and put an end to the syndicate once and for all. As well as learning who the mysterious leader of the organization is.
